| Biological Indicators | Enzyme Indicators | |
| Time for results | > 7 days | 60 seconds |
| Data available | Binary | Quantitive values |
| Variation | -50-300% | < 15% |
| Source | Bacterial Spores | Enzymes |
Enzyme Indicators offer a range of advantages over traditional Biological Indicators. One of the major benefits is Enzyme Indicators’ ability to provide clear, quantifiable results in seconds rather than days. This means users can have full confidence in the effectiveness of their bio-decontamination processes, which in turn leads to improved efficiency and reduced costs for these critical activities.
Traditional Biological Indicators require a seven-day or more incubation period before they can provide a result as to whether a gaseous bio-decontamination process has failed. By contrast, Enzyme Indicators give answers in just 60 seconds, providing for reduced costs, immediate batch verification and reduced risk that products will have to be destroyed.
Because Enzyme Indicators offer detailed, quantifiable data as opposed to the binary pass/fail information Biological Indicators deliver, this allows users to create data on their activities. In turn, this can be used to identify areas for bio-decontamination cycle improvement through our Athena™ software.
How Pfizer utilises Enzyme Indicator technology for bio-decontamination validation
Enzyme Indicators in Aseptic Production Environment
Champions Enzyme Indicators
Protak Scientific is the manufacturer of a rapid validation technology for gaseous bio-decontamination using ‘Enzyme Indicators’, developed in collaboration with Public Health England (now the UK Health Security Agency). One of our largest sectors is pharmaceutical manufacturing where we partner with over 80% of the largest pharmaceuticals.
We provide validation consultancy to multiple sectors where bio-decontamination is critical to ensure safety and efficacy. Our Athena™ software delivers real-time quantifiable results for cycle efficacy, with advanced reporting capabilities and enhanced audit and review features that ensure all operations meet compliance requirements.
These services help companies design manufacturing facilities, build bespoke equipment or manage quality assurance of pharmaceutical production, providing clients with the most effective method of bio-decontamination validation for any clean room setting or sterile environment.
Read about the advantages and benefits of using our Enzyme Indicators for your H₂O₂ bio-decontamination validation processes.
Biological Indicators vs Enzyme Indicators at a glance.
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